This manuscript explores the different components of flow, wall shear stress (axial and circumferential) and flow vortices, globally, along the ascending aorta (using 3D maps). Also, we investigated the different behavior of these parameters in the different valvular phenotypes and in the different ascending aortic morphotypes to obtain the main determinants of aortic dilatation in this population. We concluded that an eccentric jet and increased axial wall shear stress in the proximal aorta, mainly observed in the RL-phenotype, may determine the root dilatation morphotype, whereas increased rotational and vortical flow and circumferential WSS in mid and distal ascending aorta in the RN-phenotype may determine the ascending dilatation morphotype.
To close the gap outlined above, learners 'need' to know other risk factors associated to aortic dilatation in bicuspid aortic valve patients:
- We explored for the first time the global distribution (using 3D maps) of the different parameters of flow and deformation.
- We obtained through multivariate analysis the main determinants associated with aortic dilatation.
- Our findings may constitute the basis of future longitudinal studies that allow the selection of patients at greater risk of aortic dilatation and events at follow-up.
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Please see the bibliography at the end of the journal article.