JCMR 2020; 22:89. Clinical application of free-breathing 3D whole heart late gadolinium enhancement cardiovascular magnetic resonance with high isotropic spatial resolution using Compressed SENSE (CME)


Currently available free-breathing 3D LGE techniques suffer from long imaging time (between 6 and 16 minutes), especially when aiming to provide readouts with submillimetre high isotropic spatial resolution, or require extensive postprocessing, which questions their usefulness in clinical routine.


What is the ideal state/ if the problem is gone? A 3D free-breathing LGE sequence with high isotropic resolution in a short scan time without extensive postprocessing would be more applicable in clinical routine.


Purpose/ Objective

The proposed Compressed SENSE accelerated free-breathing LGE technique enables for the first time high isotropic spatial resolution in an acceptable scan time without the necessity of extensive postprocessing while providing improved depiction of left ventricular hyperenhanced lesions.


Learning Objectives

To close the gap outlined above

1. Learners need to know about: 3D LGE imaging.

2. Learners need to know how to apply: 3D LGE imaging.


Accreditation Statement
The Society for Cardiovascular Magnetic Resonance (SCMR) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.


Credit Designation Statement
The Society for Cardiovascular Magnetic Resonance (SCMR) designates this Journal-based CME activity for a maximum of 1.0 AMA PRA Category 1 Credit (s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


Instructions for Claiming CME

  • Read and fully comprehend the article
  • Complete the post-activity evaluation
  • A certificate of completion will be available once the evaluation is submitted


Financial Disclosures

The planners and faculty for this activity did not have any relationships to disclose unless listed below:

Dr. Pennig receives research funding from Philips Healthcare.


Disclosure of Commercial Support

This activity received no commercial support.



Piehler KM, Wong TC, Puntil KS, Zareba KM, Lin K, Harris DM, et al. Free-breathing, motion-corrected late gadolinium enhancement is robust and extends risk stratification to vulnerable patients. Circ Cardiovasc Imaging. 2013;6:423-32. Bratis K, Henningsson M, Grigoratos C, Dell’Omodarme M, Chasapides K, Botnar R, et al. Image-navigated 3-dimensional late gadolinium enhancement cardiovascular magnetic resonance imaging: Feasibility and initial clinical results. J Cardiovasc Magn Reson. 2017;19:97. Ginami G, Neji R, Rashid I, Chiribiri A, Ismail TF, Botnar RM, et al. 3D whole-heart phase sensitive inversion recovery CMR for simultaneous black-blood late gadolinium enhancement and bright-blood coronary CMR angiography. J Cardiovasc Magn Reson. 2017;19:94 Akçakaya M, Rayatzadeh H, Basha TA, Hong SN, Chan RH, Kissinger K V., et al. Accelerated late gadolinium enhancement cardiac MR imaging with isotropic spatial resolution using compressed sensing: Initial experience. Radiology. 2012;264:691-9. Basha TA, Akçakaya M, Liew C, Tsao CW, Delling FN, Addae G, et al. Clinical performance of high-resolution late gadolinium enhancement imaging with compressed sensing. J Magn Reson Imaging. 2017;46:1829-1838. Kino A, Zuehlsdorff S, Sheehan JJ, Weale PJ, Carroll TJ, Jerecic R, et al. Three-dimensional phase-sensitive inversion-recovery turbo FLASH sequence for the evaluation of left ventricular myocardial scar. Am J Roentgenol. 2009;193:381-8. Lintingre P-F, Nivet H, Clément-Guinaudeau S, Camaioni C, Sridi S, Corneloup O, et al. High-Resolution Late Gadolinium Enhancement Magnetic Resonance for the Diagnosis of Myocardial Infarction With Nonobstructed Coronary Arteries. JACC Cardiovasc Imaging. 2020;13:1135-1148.

Course Information
Course Date:
February 01, 2021
Accreditation Council For Continuing Medical Education
Total General Hours: 1.00
SCMR Member Price:$0.00
Non-Member Price:$10.00